Our Lipase/Esterase collection

Robust, selective lipases for hydrolysis, esterification, and advanced biocatalytic reactions at scale

Lipase Enzyme Panel

Enhance your hydrolysis, esterification, transesterification, or aminolysis with our lipases / esterases. Our lipases are available in both free and immobilized format, depending on your needs.

Proven Product Performance & Innovation

PROCESS CHEMISTRY

Scalable Biocatalysis: Producing non-natural compounds

We all have been there: Your synthetic route for a novel intermediate is established, but the efficiency has hit a ceiling and process economics are projected to break at scale. The ever-recurring question: Is biocatalysis an alternative worth thinking about without major engineering efforts, especially for non-natural compounds?

PROCESSING AID

How can you eliminate limiting impurities in DSP without compromising your API yield?

In API synthesis and pharmaceutical manufacturing, removing persistent, structurally related impurities remains a critical challenge. Traditional chemical purification steps occasionally lack the necessary selectivity, leading to significant product loss and high overhead in downstream processing (DSP)...

SUPERIOR PERFORMANCE

My enzyme needs higher thermostability to beat all competitors’ products in the market

You are almost there: your candidate enzyme is highly active and performs well in development, but its thermostability still falls short of market requirements. In feed applications, insufficient thermal tolerance during processing can directly impact product performance, process robustness...

Versatile and scalable reactions

Lipases are robust serine hydrolases that work in both aqueous and non-aqueous systems, tolerating organic solvents across a wide range of conditions. They enable hydrolysis, esterification, transesterification, and interesterification with excellent selectivity and a proven track record at industrial scale.

Free Lipase Panel (9 enzymes, mg scale):

BTL2 · CALA · CALB (+ variant) · CTL · RML · CRL3 · CRL4· TLL

Custom screening support available.

Enhanced stability and selectivity

Enhanced stability, reusability, and process control for demanding applications beyond typical CalB.

Our Pichia-expressed lipases perform in organic solvents, continuous-flow systems, at elevated temperatures, and come in superior purity. Developed jointly with Bisy and ChiralVision.

Immobilized Lipase Panel (7 enzymes, mg scale):

BTL2 · CALB (variant) · CRL3 · CRL4 · CTL · RML · TLL

Custom screening support available.

From mg screening to kg enzyme powder supply

Start with milligram-level enzyme tests, then move to kilogram powder quantities for pilot and production runs. Curated panels, reliable supply, and scale-ready delivery - all from one partner.

Check out our other enzyme products

Lipases belong to the most performant biocatalysts for a reason

If existing lipases CalB lack the performance you need, our Lipase Enzyme Panels are worth a look covering both existing and novel lipases. Connect with Rainer and see how our biocatalysts can help.