Enzyme Discovery
Find nature's most promising enzymes for your target reaction with Freedom-to-operate
Key Benefits of Enzyme Discovery
01
Find a suitable enzyme capable of catalyzing the target reaction
02
Secure a freedom-to-operate enzyme, especially in crowded IP space
03
Obtain a better starting point for your application, reducing/avoiding enzyme engineering efforts
04
Inform enzyme engineering campaigns thanks to data of sequence-diverse homologs
- DISCOVERY WORKFLOW
What makes our enzyme discovery stand out
From intelligent sequence navigation to lab-ready enzyme panels, we combine AI, bioinformatics, literature and patent parsing, and structural iology to deliver enzymes that are producible and perform.
Advanced Bioinformatics
Nature holds billions of undiscovered enzyme sequences. Our advanced bioinformatic pipeline analyzes characteristic motifs, evolutionary relationships, and mutational patterns to ensure a diverse selection of relevant enzymes.
AI-powered scoring
Looking for the needles in the haystack. We employ multi-layered algorithmic scoring of predicted fold, activity, robustness and solubility to each enzyme candidate before anything goes near a lab.
Structural biology
Sequence alone doesn't tell the full story. We also search for structural homologs to spot exotic candidates and model enzyme structures to evaluate ligand compatibility, backbone fit, and potential inhibitors to make sure only the most promising candidates move forward.
Custom enzyme panel
Discovery is only complete when performance is proven in the lab. Produced in pro- or eukaryotic hosts, we deliver your shortlisted enzymes in ready-to-scren panels as frozen lysate, lyophilized powder, or cryo-stocks shipped worldwide.
- CASE STUDIES
Proven Results with Enzyme Innovation
NOVEL PATHWAYS
How to make my strain produce the product I need?
For strain engineers developing novel pathways, pathway feasibility starts long before host engineering. Enzyme discovery, substrate compatibility, cofactor requirements, and IP freedom-to- operate can determine whether a pathway is commercially viable or blocked by technical constraints. Still, enzyme evaluation is often overlooked during early strain design, resulting in costly redesign cycles later in development...
ALTERNATIVE SYNROUTES
Can biocatalysis enable an improved synthesis route?
For process chemists developing Active (Pharmaceutical) Ingredients, route scouting and optimization becomes challenging when synthesis pathways rely on costly starting materials and catalysts, multiple (de-)protection steps, low-yield transformations...
DRUG DISCOVERY
How can I get to my metabolite faster using enzymes?
In drug discovery, the final sprint from lead optimization to candidate selection often depends on rapidly accessing metabolites, analogs, and late-stage functionalized derivatives. You often face the same, very familiar challenge...
- Others Services
The one-stop shop to deliver all your enzyme needs
Starting with the end in mind
Aminoverse's Enzyme Discovery is tuned to each customer's final application, the respective IP landscape, and wet lab capabilities.
Find out if Enzyme Discovery is right for you in a call with David.