UPOs: Efficient oxygenation at scale

Unlock biocatalytic oxyfunctionalization with our 77 Unspecific Peroxygenase collection - ready-to-use, IP-free, and scalable from mg to kg.

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UPO Enzyme Panel

Unlock new biocatalysis with the largest collection of Unspecific Peroxygenases worldwide for the oxyfunctionalization of APIs, Key Intermediates, F&F compounds, novel materials, ingredients, agro- and speciality chemicals

Proven Product Performance & Innovation

🏭 PROCESSING AID

Enhancing Industrial Processing with Tailored Enzyme Aids

Aminoverse collaborated with an industrial processing company...

🧪 ALTERNATIVE SYNROUTES

Developing Alternative Enzyme-Driven Synthetic Routes Using Biocatalysis

Aminoverse worked with a chemical development team to...

🔄 HYBRID SOLUTIONS

Combining Chemistry and Biocatalysis for Superior Process Performance

Aminoverse collaborated with a chemical manufacturing company to integrate...

UPO enzyme advantages

Powerful, versatile, and scalable enzymes to unlock new chemistry, simplify synthesis routes, and accelerate your reactions.

Unlock New Chemistry

Convert challenging C-H bonds under mild, sustainable conditions with UPOs.

Made for Chemists

Ready-to-use lyophilized enzymes-no prior enzyme knowledge required.

Broad Substrate Scope

Efficiently oxidize diverse substrates with variable regio- and enantioselectivity.

Reactions That Scale

Biocatalytic reactions are scalable from mg to kg with simple hydrogen peroxide supplementation.

No IP Hassles

All UPOs are free of third-party IP-focus on your reaction, not licensing.

From Unspecific to Specific

Tailor UPOs for even higher yield and stability with over 10 years of enzyme engineering expertise.

Cheap Oxygen Supply

Hydrogen peroxide as only required co-factor. Say goodbye to NAD(P)H and molecular oxygen.

Unmatched Quality

Our UPOs are produced in Pichia pastoris - outcompeting E. coli-based preparations in yield and performance.

Robust and immobilizable

UPOs come with inherent stability to organic solvents, storage and perform well when immobilized.

From mg screening to kg enzyme powder supply

Start with milligram-level enzyme tests, then move to kilogram powder quantities for pilot and production runs. Curated panels, reliable supply, and scale-ready delivery-all from one partner.

P450 vs UPO

Cytochrome P450 Monooxygenases expanded the chemist’s toolkit and made their way into various biocatalytic applications. They do however come with plenty of drawbacks for cost efficient API production, especially at scale. UPOs represent the next generation of oxyfunctionalizing enzymes – with higher turnover, simpler handling and improved process robustness.

UPO applications

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UPOs perform fascinating chemistry

I firmly believe UPOs can change the way we make chemistry and possibly these enzymes are the P450s we all were waiting for. If you are interested in screening our UPO Enzyme Panel, let's have a chat.